The 12 Best Wrinkle Fillers That Work Like a Time Machine (2024)

This serum is jam-packed with peptides and hydrating ingredients that not only treat signs of aging in the long term, but also in the short term, too. The goal is to strengthen and plump the skin, reducing the appearance of fine lines in just fifteen minutes.

Key ingredients: Collagen peptides, amino acids, hyaluronic acid

Amazon rating: 4.3/5 stars

An Amazon reviewer says: “My face and lines around my eyes are plumped about 10 mins after applying it. The appearance of wrinkles diminished and my face just firmed up a lot. I applied it every night for about two weeks now, and today my aesthetician wondered what I have done to my face. She said I looked so great but couldn’t tell what made the difference.... I’m purchasing a second one now!”

Many skin care ingredients oftentimes sit on top of the barrier, which can prevent seeing noticeable results. That’s why this serum was formulated with ingredients specifically designed to deeply penetrate the skin, plumping fine lines and repairing damage.

Key ingredients: Hyaluronic acid, peptide proteins, niacinamide

Amazon rating: 3.9/5 stars

An ELLE editor says: “I’m concerned about fine lines on my forehead but staving off Botox for as long as possible (and honestly, hopefully forever). With this being said, I’ve been hyper-focused on products that can fill in my wrinkles. People rave about Dr. Dennis Gross and many say he is the dermatologist to see in NYC. His products are known for their efficacy, which is why I was okay dropping $75 on a product. It deeply penetrates into your skin, minimizing wrinkles immediately with long-lasting changes you’ll see over time.” —Danielle James, digital beauty director

Looking for an instant lift? This serum can be used around the eyes or on the entire face, and it uses a tightening ingredient derived from clay that helps smooth lines instantly. The effects last ten hours or so, which makes it a perfect prep step before important events.

Key ingredients: Collagen, peptides, silicate

Amazon rating: 3.8/5 stars

An Amazon reviewer says: “I’ve been using this for about a week now. What I found was that it does what it says it will do. I have bags under my eyes, and to make it work, it took me a few tries to place it where it had the most effect. In my case, not directly on the bags, but a little under the bags. It took at least 80% of the bags and made them disappear. It lasted for 8 to 10 hours. You can feel it working. A little fountain of youth that temporarily slows down the effects of time.”

If you’re fine with your fine lines and wrinkles on most days, but want a little extra coverage before a big day, this product gives the illusion of smoother skin, thanks to its light-diffusing tones. While it’s not a long-term fix, it does a remarkable job of masking signs of aging underneath makeup.

Key ingredients: Glycerin

Target rating: 3.9/5 stars

A Target reviewer says: “Love this for under eye area to help with lines. It’s the best I tried and can be worn under or over makeup for touch ups.”

If you’re serious about reducing signs of aging over time, the best ingredient to help with that journey is retinol. While it provides great results over time, it also instantly plumps the skin, reducing fine lines quickly, too.

Key ingredients: Retinol, hyaluronic acid

Ulta rating: 4.3/5 stars

An Ulta reviewer says: “I saw results after 2 weeks. I used to have two deep vertical wrinkles in between my eyebrows and they’re almost invisible now. It’s very hydrating and smooth. Highly recommend this product!!”

This product went viral on TikTok for being “Botox in a bottle,” thanks to its keen ability to reduce fine lines after just a few uses. The key ingredients plump the skin, hydrating and repairing the skin.

Key ingredients: Argireline peptide complex

Ulta rating: 4/5 stars

An Ulta reviewer says: “I have been using this every evening on my forehead for one week so far, and oh my God it works!! The serum is watery so a little goes a long way but I pat it into my forehead and let dry a bit before adding my next product. My deep wrinkles are fading! Would recommend!”

When your skin is dry, it can exacerbate the appearance of fine lines, wrinkles, and uneven skin. This serum is not only packed with plumping ingredients, but it also has moisturizing properties that add an instant glow.

Key ingredients: Hyaluronic acid, collagen, peptides

Amazon rating: 4.6/5 stars

An Amazon reviewer says: “You need to use this product continuously before seeing a difference. It is expensive, but you don’t use much at a time and it will last a long time. I’ve been using it daily or every other day, and I am noticing some changes in my skin’s appearance. I also have very sensitive skin and it hasn’t bothered that at all.”

This product is somewhere between a makeup primer and a skin care product. It uses vitamin C to brighten the skin, while hyaluronic acid plumps the skin. This product is designed to fill in wrinkles, leaving you with an even base for makeup.

Key ingredients: Vitamin C, hyaluronic acid

Amazon rating: 4.2/5 stars

An Amazon reviewer says: “I am very happy with the product. I have immediately felt that my skin looks better and is more hydrated. Love it.”

This product went viral on TikTok after users showed how quickly it erased wrinkles and tightened the skin. While the results aren’t permanent, the infused vitamins help nourish the skin barrier for great results over time.

Key ingredients: Vitamin C, vitamin E, vitamin B5

Amazon rating: 3.7/5 stars

An Amazon reviewer says: “If you are looking for a skin tightener, this is for you! It's a game-changer!!! I thought it was just me, but people were asking what I did to my skin. I kept it a secret for sometime, then I turned my sister on to this, then my adult daughters. THEY WENT CRAZY FOR THIS! They ALL purchased this, and absolutely love it!!!”

This product targets fine lines and wrinkles in three ways: smoothing their appearance immediately, fading them overtime, and preventing them in the future. The brand’s targeted NIA-114 peptides plump and heal the skin around the mouth, eyes, and forehead.

Key ingredients: Patented NIA-114, peptides

Amazon rating: 4.2/5 stars

An Amazon reviewer says: “I’ve been using this for a month now. I was apprehensive at purchasing an expensive product I have never used. I have say, I use it every night and can tell a difference and my skin looks smooth. The viable lines I had have shrunk and barely visible now. This stuff doesn’t make your skin tight and actually makes it feel soft. I think it works wonderful for a night cream. Highly recommend it if you’re an older woman and have deep wrinkles you need to fade.”

Created to target expression lines around the eyes and forehead, this serum lifts the skin and plumps up deeper lines. It works in as little as fifteen minutes, but over time, the ingredients help fade signs of aging.

Key ingredients: Magnesium, peptides, adenosine, glycolic acid

Ulta rating: 3.7/5 stars

An Ulta reviewer says: “I think this product is underrated. I have bought it several times. I use it as indicated and am 37 with no forehead wrinkles. Thank you, Dr. Brandt!”

This targeted serum was created to plump fine lines and wrinkles, offering an instant boost to the skin. Plus, the hydrating and repairing ingredients also work to moisturize the skin and add a glow.

Key ingredients: Hyaluronic acid, peptides, squalane

Dermstore rating: 4.1/5 stars

A Dermstore reviewer says: “Wiped my wrinkles away—great stuff for older skin. I'm coming up on 38 and working my tail off, so stress comes up. Wrinkles come with that. This helps out a lot!”

Dr. Karan Lal is a double-board certified dermatologist and fellowship-trained cosmetic dermatologist, based in Scottsdale, Arizona.

Bryan Barron is the Director of Skin Care Research at Paula’s Choice.

Dr. Dennis Gross is board-certified dermatologist, dermatologic surgeon, and brand founder.

When we think of “fillers,” we often think of injectables administered in a medical office. However, wrinkle fillers are actually topical skin care products that target signs of aging. “Wrinkle-filling serums are products that are composed of peptides, hyaluronic acid, collagen, and even sometimes retinol. The purpose of these serums is not to replace a filler, but to stimulate collagen, hydrate the skin, and soften the appearance of fine lines in the area where the product is applied,” says Dr. Lal.

These products can work in both the long term, minimizing fine lines, or immediately. “Wrinkle-filling serums are typically specialized skin care products that often make an immediate difference in the appearance of wrinkles. Depending on the formula, they may have a temporary filling effect, a soft-focus or blurring effect, or interact with factors in skin that lead to muscle contractions and their resulting expression lines. These products may be applied over or under other skin care staples like moisturizers, serums, and eye creams,” adds Barron.

Fine lines and wrinkles are completely normal signs of getting older. But knowing what causes them can help reduce their appearance, if that’s what you choose. “Wrinkles occur from repetitive facial movements and muscles that are active in the skin for facial expression. For example, smiling causes the formation of crows feet overtime. Over a long period of time it can cause the formation of the 11 lines. Lines often occur from a combination of repetitive movements and loss of collagen leading to etched in skin lines,” says Dr. Lal.

Our skin is made up of building blocks that naturally fade as we age. “Fine lines and wrinkles are caused by the breakdown of essential proteins collagen and elastin in the skin. Collagen and elastin are the building blocks of our skin and help to keep it smooth and resilient. However, as we age, these fibers start to naturally break down and degrade, which causes the skin to lose its strength and elasticity and triggers the formation of fine lines and wrinkles,” says Dr. Gross.

Wrinkles can also be exacerbated by damage to the skin, like what occurs with prolonged exposure to the sun. Barron explains, “The leading cause of wrinkles and fine lines is cumulative UV light exposure, both from intentional tanning–indoors or outside–and from the day-to-day small exposures we get over the years. This is why a broad-spectrum sunscreen is the best anti-wrinkle product you can use. Without it, skin is left vulnerable, and no amount of wrinkle-filling serum will be of much help. Secondary causes of fine lines and wrinkles include blue light exposure–including from our smartphones, laptops, and tablets–airborne pollutants, and muscle movement that comes from facial expressions such as smiling, frowning, and squinting.”

While no cream can instantly rewind the clock, topical products can and do make a significant impact on reducing signs of aging. Some wrinkle fillers work at getting instant yet short-lived results, while others work to reduce fine lines over time. However, depending on the ingredients, both types of products can work in both the long and short-term. “Topical products do have the ability to soften and hydrate the skin which can give the skin a more plump appearance, therefore softening the presence of wrinkles and fine lines,” says Dr. Lal.

The effectiveness of these types of products can come down to both the ingredients, and how they are formulated. “It’s always important to look for a product that features clinically proven active ingredients and advanced delivery systems. The delivery system is critical for a product to be efficacious and deliver real results. One of the skin’s incredible benefits is to protect us from outside pathogens, which is why we need a product designed to penetrate the intercellular matrix and stimulate cell receptors deep within the skin layers,” says Dr. Gross.

Barron adds, “The effect [of some wrinkle fillers] is temporary, but ongoing use coupled with daily sunscreen use can absolutely reduce the look of wrinkles and keep skin from reverting to its previous ‘aged’ appearance. Even better if you include other products in your routine whose formulas also work in their own distinct ways to soften lines. Examples would be leave-on exfoliants containing alpha, beta, or polyhydroxy acids, antioxidant-packed serums, retinoid products, and peptide-spiked treatments. Each of these works via different pathways to help repair and rebuild skin’s supportive elements so its surface regains a youthful smoothness, bounce, and resilience that forestalls further wrinkling.”

When you’re assessing a wrinkle filler product, ingredients are key. “My favorite serums for wrinkles are those that contain peptides and hyaluronic acid. Both of these hydrate and nourish the skin, providing a plump, dewy look,” explains Dr. Lal.

The ingredient list may look a little different if you're looking for instant results. “The instant smoothing and blurring effect of silicone elastomers is helpful, so ingredients such as dimethicone/vinyl dimethicone crosspolymer or polysilicone-11 are worth seeking out. We also like line-smoothing signal peptides such as tridecapeptide-1 and sh-polypeptide-121 since these target instant and long-term line-smoothing. Various forms and molecular weights of classic hyaluronic acid can also be helpful due to their smoothing and plumping action. Another good one similar to hyaluronic acid–or its salt form, sodium hyaluronate–is polyglutamic acid,” adds Barron.

Because wrinkle fillers are formulated with different ingredients, the time it takes to see results can vary. “This will vary by formula and the concentration of key actives. For some wrinkle fillers, results will be seen from immediately to within 15 minutes of use; for others, the effect may take an hour or two to become visible. Results should last for a few hours, and you should see a maintenance of fine lines and more apparent wrinkles with ongoing use, preferably twice daily, morning and evening,” says Barron.

If you are using a skin care product, patience is key. “Wrinkle-filling serums take approximately 12 weeks to start showing signs of improvement. Consistency is very important, especially when it comes to softening the appearance of fine lines and wrinkles,” adds Dr. Lal.

If you are considering a wrinkle filler as an alternative to in-office anti-aging treatments like Botox, there are some important factors to consider. “There is no replacement for Botox or filler. Some people say these are the next best thing. Topical products are often used to maintain and prolong the results of injectables like Botox and filler,” says Dr. Lal.

Barron adds, “Topical wrinkle fillers do not penetrate as far as Botox and usually act on different channels of the muscle contraction process that either complement or enhance what Botox or Dysport can do. Generally, a topical wrinkle filler can be a good pairing with dermatologic injections since their use helps prolong results, letting you go longer between treatments. This saves time and money.”

However, it is also important to remember that despite their efficacy, injectables have their own drawbacks. “While injectable procedures are amazing for quick and dramatic results, they are costly and pose potential risks such as bruising, swelling, and infection. In my practice, I have seen the hesitancy for needles firsthand because of those factors, so I wanted to create a serum for my patients who were looking to support their skin health with topical ingredients that stimulate the skin’s own production of collagen. The topical option is a much more affordable way to treat fine lines and wrinkles, and can be done from the comfort of your own home,” explains Dr. Gross.